SCHEMBL9519965

SCHEMBL9519965

C#CCn1c(C)[c]sc1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ADORA2B P29275 2/20 0.30
GLA P06280 1/20 0.30
BLM P54132 1/20 0.30
AMY1A P0DUB6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9519680 0.73 MAOB (0.30)
SCHEMBL9520707 0.67 CNR2 (0.33) LMNARAB9ASMN1; SMN2ADORA2BGLA
SCHEMBL9573801 0.65 RAB9A (0.39) LMNARAB9ASMN1; SMN2ADORA2BGLA
SCHEMBL9520703 0.64 CNR2 (0.32) LMNARAB9ASMN1; SMN2
SCHEMBL1629499 0.64 ADORA2B (0.39) LMNARAB9ASMN1; SMN2ADORA2BGLA
SCHEMBL9521296 0.62 TKT (0.35)
SCHEMBL9583043 0.62 CNR2 (0.31)
SCHEMBL9520853 0.61 CNR2 (0.30)
SCHEMBL9519935 0.60
SCHEMBL21531890 0.60 ADORA2B (0.38) RAB9AADORA2BGLABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300898-B1 PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-03-10 EP claimed
EP-0300898-B1 PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-03-10 EP disclosed
EP-0300898-A1 Pyrethrinoid derivatives containing an N-heterocycle, processes and intermediates for their preparation, their use as pesticides and compositions containing them ROUSSEL-UCLAF (FR) 1989-01-25 EP disclosed