SCHEMBL9520703

SCHEMBL9520703

C#CCn1c(C)c([CH2])sc1=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.32
RAB9A P51151 2/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9520707 0.81 CNR2 (0.33) CNR2RAB9AMEN1NPC1ALDH1A1
SCHEMBL9583043 0.75 CNR2 (0.31) CNR2MEN1ALDH1A1KMT2A
SCHEMBL9521296 0.75 TKT (0.35) CNR2
SCHEMBL9520847 0.74
SCHEMBL9520853 0.67 CNR2 (0.30) CNR2
SCHEMBL3032222 0.64 L3MBTL1 (0.58) RAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL9519965 0.64 LMNA (0.31) RAB9ALMNASMN1; SMN2
SCHEMBL9573801 0.64 RAB9A (0.39) RAB9AMEN1NPC1ALDH1A1KMT2A
SCHEMBL13281475 0.63 ADORA2B (0.35) RAB9ALMNASMN1; SMN2
SCHEMBL1629499 0.62 ADORA2B (0.39) RAB9ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0300898-B1 PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1993-03-10 EP claimed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US claimed
US-5008281-A Insecticides, miticides, nematocides ROUSSEL UCLAF (FR) 1991-04-16 US disclosed
US-4925862-A PESTICIDES ROUSSEL UCLAF (FR) 1990-05-15 US disclosed