Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521572 | 0.87 | LMNA (0.34) | PTPN11ALDH1A1L3MBTL1 | |
| SCHEMBL9522911 | 0.87 | NPC1 (0.31) | ALDH1A1 | |
| SCHEMBL9521073 | 0.85 | NOTUM (0.35) | — | |
| SCHEMBL7888767 | 0.78 | MEN1 (0.32) | ALDH1A1 | |
| SCHEMBL10985357 | 0.77 | TSHR (0.35) | PTPN11L3MBTL1 | |
| SCHEMBL9523542 | 0.76 | MAPT (0.35) | ALDH1A1 | |
| SCHEMBL9494830 | 0.74 | NOTUM (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL9519617 | 0.74 | LMNA (0.34) | ALDH1A1 | |
| SCHEMBL9468954 | 0.74 | MAPT (0.35) | ALDH1A1 | |
| SCHEMBL10410672 | 0.73 | TDP1 (0.41) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |