Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995220 | 0.86 | HPGD (0.42) | TSHRMAPTLMNAWDR5POLB | |
| SCHEMBL9706594 | 0.78 | OPRK1 (0.30) | OPRK1 | |
| SCHEMBL11207046 | 0.78 | GRM7 (0.41) | — | |
| SCHEMBL9519992 | 0.77 | PTPN11 (0.31) | L3MBTL1PTPN11 | |
| SCHEMBL7888644 | 0.76 | JAK2 (0.33) | — | |
| SCHEMBL7888767 | 0.76 | MEN1 (0.32) | — | |
| SCHEMBL9706605 | 0.76 | TSHR (0.34) | TSHRMAPTLMNAKDM4EHPGD | |
| SCHEMBL10985184 | 0.74 | OPRK1 (0.34) | TSHROPRK1MAPTLMNACA12 | |
| SCHEMBL9522911 | 0.74 | NPC1 (0.31) | MAPT | |
| SCHEMBL24152095 | 0.73 | LMNA (0.38) | TSHRMAPTLMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4561880-A | 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |