Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | NPC1 | O15118 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | CES2 | O00748 | 2/20 | 0.62 |
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | STS | P08842 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | VNN1 | O95497 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17041600 | 0.92 | RAB9A (0.63) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL31414638 | 0.89 | CES2 (0.77) | RAB9ANPC1CES2CES1STS | |
| SCHEMBL4823687 | 0.89 | CES2 (0.77) | RAB9ANPC1CES2CES1STS | |
| SCHEMBL31286476 | 0.88 | STS (0.62) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL2784166 | 0.88 | ALDH1A1 (0.70) | RAB9ANPC1ALDH1A1CES2CES1 | |
| Hydrochloric Acid SCHEMBL27733557 | 0.87 | CES2 (0.74) | RAB9ANPC1CES2CES1STS | |
| SCHEMBL30414806 | 0.84 | MEN1 (0.69) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL755443 | 0.84 | MEN1 (0.69) | RAB9ANPC1ALDH1A1CES2CES1 | |
| SCHEMBL4820908 | 0.84 | CES2 (0.69) | RAB9ANPC1CES2CES1STS | |
| SCHEMBL1258944 | 0.83 | CES2 (0.74) | RAB9ANPC1CES2CES1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299379-B1 | PENTADIENAMIDE PAF-ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| US-4975438-A | ANTICOAGULANT | HOFFMANN-LA ROCHE INC. (US) | 1990-12-04 | — | — | US | disclosed |
| EP-0299379-A1 | Pentadienamide PAF-antagonists | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-18 | — | — | EP | disclosed |
| US-4788206-A | CARDIOVASCULAR DISORDERS, PLATELETS | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |