Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520171 | 0.99 | ALDH1A1 (0.72) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9518803 | 0.95 | ALDH1A1 (0.74) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9518762 | 0.90 | ALDH1A1 (0.70) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9247091 | 0.89 | ALDH1A1 (0.68) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9519885 | 0.85 | ALDH1A1 (0.72) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7960637 | 0.83 | LMNA (0.57) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7973675 | 0.83 | LMNA (0.57) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7960503 | 0.83 | LMNA (0.57) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7960627 | 0.83 | LMNA (0.57) | MEN1KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL7960449 | 0.83 | LMNA (0.57) | MEN1KMT2ASMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350467-B1 | Pharmacologically active benzimidazole derivatives | DOMPE FARMACEUTICI SPA (IT) | 1993-12-29 | — | — | EP | disclosed |
| US-4971980-A | ANTIHISTAMINES | DOMPE FARMACEUTICI S.P.A. (IT) | 1990-11-20 | — | — | US | disclosed |