Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 10/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522911 | 0.80 | CYP2C19 (0.41) | RXRA | |
| SCHEMBL4407340 | 0.80 | RXRA (0.48) | RXRAPDK2NPC1RAB9A | |
| SCHEMBL10842199 | 0.75 | GAA (0.47) | RXRAMEN1KMT2A | |
| SCHEMBL8522801 | 0.74 | RXRA (0.60) | RXRA | |
| SCHEMBL10460035 | 0.74 | RXRA (0.34) | RXRAPDK2 | |
| SCHEMBL8523207 | 0.73 | HNF4A (0.47) | RXRANPC1RAB9AMEN1KMT2A | |
| SCHEMBL8523204 | 0.73 | HNF4A (0.47) | RXRANPC1RAB9AMEN1KMT2A | |
| SCHEMBL9586891 | 0.72 | KMT2A (0.47) | RXRARAB9AKMT2A | |
| SCHEMBL8776390 | 0.71 | RXRA (0.44) | RXRAMEN1KMT2AGRM1 | |
| SCHEMBL10356133 | 0.71 | CYP26A1 (0.45) | RXRANPC1RAB9ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382076-B1 | PHENYLHYDRAZONES, THEIR PREPARATION AND MEDICAMENTS AND COSMETICS MANUFACTURED THEREFROM | BASF Aktiengesellschaft (DE) | 1993-01-20 | — | — | EP | disclosed |
| EP-0382076-A1 | Phenylhydrazones, their preparation and medicaments and cosmetics manufactured therefrom | BASF Aktiengesellschaft (DE) | 1990-08-16 | — | — | EP | disclosed |