Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.68 |
| ▸ | CHUK | O15111 | 2/20 | 0.53 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12660084 | 0.81 | NPC1 (0.62) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL13889828 | 0.81 | CASP3 (1.00) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL14914829 | 0.78 | SMN1; SMN2 (0.55) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL9987876 | 0.78 | L3MBTL1 (0.50) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL7433112 | 0.78 | BCHE (0.58) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL13606307 | 0.76 | CASP3 (0.77) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL2642361 | 0.76 | PDK2 (0.49) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL1281643 | 0.76 | NPC1 (0.64) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL17071980 | 0.76 | RAB9A (0.49) | L3MBTL1PDK2ALDH1A1HSD17B10MAPT | |
| SCHEMBL9520118 | 0.75 | ESR1 (0.47) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140225027-A1 | Silver Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | DOW CORNING CORPORATION | 2014-08-14 | — | — | US | disclosed |
| US-20140187783-A1 | Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | DOW CORNING CORPORATION | 2014-07-03 | — | — | US | disclosed |
| EP-0760811-B1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 MODULATORS | INST NAT SANTE RECH MED (FR) | 2009-11-18 | — | — | EP | disclosed |
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140225027-A1 | Silver Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts | ALG8, GYPA, HIRA | CASP3 4143/4885SENP8 4113/4885SENP7 4705/4885 |
| US-20140187783-A1 | Hafnium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts | HIRA, HACL2, CROCC | CASP3 4141/4885SENP8 4227/4885SENP7 4377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.