Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14465955 | 0.85 | CYSLTR2 (0.36) | CYSLTR2CYSLTR1LIPG | |
| SCHEMBL9518709 | 0.84 | CYSLTR2 (0.37) | CYSLTR2CYSLTR1LIPG | |
| SCHEMBL11081681 | 0.79 | HTR2C (0.34) | — | |
| SCHEMBL8378247 | 0.76 | TDP1 (0.34) | — | |
| SCHEMBL9950873 | 0.76 | CEL (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9860715 | 0.74 | LIPG (0.42) | LIPG | |
| SCHEMBL2177804 | 0.74 | LIPG (0.42) | LIPG | |
| SCHEMBL9949872 | 0.74 | CEL (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL9670333 | 0.72 | TDP1 (0.42) | LIPG | |
| SCHEMBL11342700 | 0.72 | APOBEC3G (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536310-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0536310-A4 | CHEMICAL COMPOUNDS. | SMITHKLINE BEECHAM CORP (US) | 1993-02-05 | — | — | EP | disclosed |
| WO-1992000279-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-01-09 | — | — | WO | disclosed |
| US-4996214-A | Respiratory systyem disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |