Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490767 | 0.86 | GAA (0.67) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| Methane SCHEMBL9226524 | 0.85 | GAA (0.65) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL7647695 | 0.85 | GAA (0.65) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL1292189 | 0.82 | GAA (0.58) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL29752821 | 0.82 | GAA (0.58) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL925918 | 0.82 | KMT2A (0.39) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL5184540 | 0.81 | CES2 (0.42) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL5184541 | 0.81 | CES2 (0.42) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL11056873 | 0.81 | GAA (0.60) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL6860676 | 0.80 | GAA (0.41) | GAAKMT2AMEN1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359710-B1 | OPTICAL BRIGHTENING AGENTS | CIBA-GEIGY AG (CH) | 1993-06-16 | — | — | EP | disclosed |
| US-5071993-A | Bis(dibenzoxayzoyl) thiophene fluorescent brighteners | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0359710-A1 | Optical brightening agents | CIBA-GEIGY AG (CH) | 1990-03-21 | — | — | EP | disclosed |