Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692154 | 0.86 | ALDH1A1 (0.45) | KMT2AMEN1PKMMAPTPDGFRB | |
| SCHEMBL3689373 | 0.85 | KMT2A (0.45) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL3130670 | 0.84 | TRPV1 (0.44) | KMT2AMAPTLMNAALDH1A1IDO1 | |
| SCHEMBL13508927 | 0.83 | KMT2A (0.39) | KMT2AMEN1PKMMAPTPDGFRB | |
| SCHEMBL3687250 | 0.83 | THRA (0.43) | — | |
| SCHEMBL9520168 | 0.82 | GAA (0.52) | KMT2AMEN1GPR35LMNAALDH1A1 | |
| SCHEMBL5416433 | 0.78 | POLB (0.50) | KMT2AMAPTGPR35ALDH1A1HPGD | |
| SCHEMBL30201064 | 0.78 | POLB (0.50) | KMT2AMAPTGPR35ALDH1A1HPGD | |
| SCHEMBL5072092 | 0.77 | TRPV1 (0.54) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL3684924 | 0.77 | THRA (0.39) | MAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620431-A1 | Novel crystals of substituted phenylalkanoic acid and production process | Asahi Kasei Pharma Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| EP-2045244-B1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID AND PRODUCTION PROCESS | ASAHI KASEI PHARMA CORP (JP) | 2013-04-03 | — | — | EP | disclosed |
| CN-102690234-A | Novel crystal forms of substituted phenylalkanoic acids and process for producing the same | ASAHI KASEI PHARMA CORP | 2012-09-26 | — | — | CN | disclosed |
| CN-101490012-B | Novel crystal of substituted phenylalkanoic acid and process for producing same | ASAHI KASEI PHARMA CORP | 2012-07-18 | — | — | CN | disclosed |
| US-7935720-B2 | Crystal of substituted phenylalkanoic acid ester and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2011-05-03 | — | — | US | disclosed |
| US-20110021593-A1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME | SHODA MOTOSHI | 2011-01-27 | — | — | US | disclosed |
| US-7838546-B2 | Crystal of substituted phenylalkanoic acid ester and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-20100234440-A1 | NOVEL CRYSTAL OF SUBSTITUTED PHENYLALKANOIC ACID ESTER AND PROCESS FOR PRODUCING THE SAME | SHODA MOTOSHI | 2010-09-16 | — | — | US | disclosed |
| US-7754752-B2 | Crystals of substituted phenylalkanoic acid and method of producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-02-25 | — | — | US | disclosed |
| US-20080070967-A1 | Novel crystal forms of substituted phenylalkanoic acids and process for producing the same | ASAHI KASEI PHARMA CORPORATION (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20070213333-A1 | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORPORATION (JP) | 2007-09-13 | — | — | US | disclosed |
| CN-101031539-A | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORP (JP) | 2007-09-05 | — | — | CN | disclosed |
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| CN-1653032-A | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI CHEMICAL IND (JP) | 2005-08-10 | — | — | CN | disclosed |
| US-6867320-B2 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-03-15 | — | — | US | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |
| EP-1477472-A1 | SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2004-11-17 | — | — | EP | disclosed |
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048893-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | KMT2A 1597/4885MEN1 4864/4885PKM 2058/4885 |
| US-20040044258-A1 | Substituted phenylalkanoic acid derivatives and use thereof | PTGER1, CYSLTR1, PTGS1 | KMT2A 2392/4885MEN1 4756/4885PKM 865/4885 |
| US-20070213333-A1 | Substituted arylalkanoic acid derivatives and use thereof | CYSLTR1, CYSLTR2, LTB4R2 | KMT2A 1597/4885MEN1 4864/4885PKM 2058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.