Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184541 | 1.00 | CES2 (0.42) | CES2ACHECES1GAAKMT2A | |
| SCHEMBL14418461 | 0.94 | CES2 (0.41) | CES2ACHECES1GAAKMT2A | |
| SCHEMBL6860676 | 0.88 | GAA (0.41) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL6860674 | 0.88 | GAA (0.41) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL5186218 | 0.83 | GAA (0.45) | ACHEGAAKMT2AMEN1HTT | |
| SCHEMBL14413578 | 0.83 | GAA (0.45) | ACHEGAAKMT2AMEN1HTT | |
| SCHEMBL9520168 | 0.81 | GAA (0.52) | GAAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL14418641 | 0.78 | GAA (0.41) | ACHEGAAKMT2AMEN1HTT | |
| SCHEMBL9007271 | 0.77 | NPC1 (0.44) | CES2ACHECES1KMT2AMEN1 | |
| SCHEMBL9178108 | 0.77 | NPC1 (0.44) | CES2ACHECES1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339700-B1 | PROCESS FOR THE PREPARATION OF BENZOTRIAZOLES | CIBA SC HOLDING AG (CH) | 2007-11-21 | — | — | EP | disclosed |
| US-20070208165-A1 | Process for the preparation of benzotriazoles | FISCHER WALTER | 2007-09-06 | — | — | US | disclosed |
| US-20070208165-A1 | Process for the preparation of benzotriazoles | FISCHER WALTER | 2007-09-06 | — | — | US | disclosed |
| US-6815550-B2 | DIAZOTIZING A 5-PERFLUOROALKYL-O-NITROANILINE WITH SULFURIC ACID AND ALKALI METAL NITRITE OR NITROSYLSULFURIC ACID; COUPLING WITH A PHENOL; AND REDUCING THE MONOAZOBENZENE INTERMEDIATE TO THE CORRESPONDING 2H-BENZOTRIAZOLE | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-11-09 | — | — | US | disclosed |
| US-20040019220-A1 | Process for the preparation of benzotriazoles | CIBA SPECIALTY CHEMICALS CORP. | 2004-01-29 | — | — | US | disclosed |
| US-6605727-B2 | Processes for the preparation of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-08-12 | — | — | US | disclosed |
| US-20030130524-A1 | Processes for the preparation of benzotriazole UV absorbers | WOOD MERVIN G (US) | 2003-07-10 | — | — | US | disclosed |
| US-20030120083-A1 | Processes for the preparation of benzotriazole UV absorbers | WOOD MERVIN G (US) | 2003-06-26 | — | — | US | disclosed |
| US-6566507-B2 | Processes for the preparation of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-05-20 | — | — | US | disclosed |
| EP-1305298-A2 | PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS | Ciba SC Holding AG (CH) | 2003-05-02 | — | — | EP | disclosed |
| US-20020035175-A1 | Processes for the preparation of benzotriazole UV absorbers | CIBA SPECIALTY CHEMICALS CORP. | 2002-03-21 | — | — | US | disclosed |
| WO-2002012202-A2 | PROCESSES FOR THE PREPARATION OF BENZOTRIAZOLE UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035175-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | CES2 1546/4885ACHE 3174/4885CES1 1296/4885 |
| US-20070208165-A1 | Process for the preparation of benzotriazoles | CBR1, CCNT1, CYP1B1 | CES2 1169/4885ACHE 415/4885CES1 2169/4885 |
| US-20030120083-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | CES2 1546/4885ACHE 3174/4885CES1 1296/4885 |
| US-20030130524-A1 | Processes for the preparation of benzotriazole UV absorbers | SULT1A1, SULT2A1, NISCH | CES2 1546/4885ACHE 3174/4885CES1 1296/4885 |
| US-20040019220-A1 | Process for the preparation of benzotriazoles | SULT1E1, SULT1A1, CYP1B1 | CES2 792/4885ACHE 964/4885CES1 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.