Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 8/20 | 0.51 |
| ▸ | GSK3A | P49840 | 4/20 | 0.51 |
| ▸ | RGS4 | P49798 | 5/20 | 0.45 |
| ▸ | RGS8 | P57771 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749771 | 0.81 | LMNA (0.47) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL23727735 | 0.77 | L3MBTL1 (0.39) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL23727737 | 0.77 | L3MBTL1 (0.39) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL5292567 | 0.73 | GSK3B (0.55) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL9519526 | 0.71 | GSK3B (0.51) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL23749770 | 0.70 | ALDH1A1 (0.45) | GSK3BKDM4EPKML3MBTL1LMNA | |
| SCHEMBL29115280 | 0.70 | HPGD (0.60) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL2573713 | 0.70 | L3MBTL1 (0.45) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL9868147 | 0.69 | KDM4E (0.49) | GSK3BGSK3ARGS4RGS8KDM4E | |
| SCHEMBL9868143 | 0.69 | L3MBTL1 (0.53) | GSK3BGSK3ARGS4RGS8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300898-B1 | PYRETHRINOID DERIVATIVES CONTAINING AN N-HETEROCYCLE, PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS PESTICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-03-10 | — | — | EP | disclosed |