Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685875 | 0.82 | ALDH1A1 (0.43) | MEN1NPC1ALDH1A1POLBMAPT | |
| SCHEMBL9744386 | 0.80 | ALDH1A1 (0.42) | MEN1NPC1ALDH1A1POLBMAPT | |
| SCHEMBL9746142 | 0.80 | ALDH1A1 (0.42) | MEN1NPC1ALDH1A1POLBMAPT | |
| SCHEMBL17969264 | 0.78 | KLKB1 (0.39) | MEN1NPC1ALDH1A1POLBMAPT | |
| Water SCHEMBL9746706 | 0.78 | ALDH1A1 (0.41) | MEN1NPC1ALDH1A1POLBMAPT | |
| SCHEMBL9521372 | 0.75 | ADRA1A (0.50) | KMT2ASMN1; SMN2 | |
| SCHEMBL10925693 | 0.66 | — | — | |
| SCHEMBL9745480 | 0.63 | ADRA1A (0.45) | — | |
| SCHEMBL9745261 | 0.63 | ADRA1A (0.45) | — | |
| Water SCHEMBL9745436 | 0.61 | ADRA1A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
| EP-0366614-A2 | Pharmaceutically active dithioketene derivatives | YUHAN CORPORATION, LTD. (KR) | 1990-05-02 | — | — | EP | disclosed |