Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.46 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 11/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520213 | 0.93 | KCNH2 (0.53) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9520277 | 0.89 | POLB (0.44) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9520390 | 0.88 | POLB (0.61) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9520477 | 0.88 | POLB (0.61) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9520487 | 0.88 | POLB (0.61) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9837385 | 0.83 | POLB (0.45) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9521387 | 0.82 | CACNA1F (0.51) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9839484 | 0.81 | KCNH2 (0.52) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9520194 | 0.81 | CACNA1F (0.70) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9520182 | 0.81 | CACNA1F (0.70) | KCNH2POLBCACNA1FMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347851-B1 | Quinolonecarboxylic acids | SHIONOGI & CO (JP) | 1993-11-10 | — | — | EP | claimed |