Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211507 | 0.86 | KCNH2 (0.43) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL9837378 | 0.86 | POLB (0.61) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL9839484 | 0.85 | KCNH2 (0.52) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL10686830 | 0.84 | CACNA1F (0.54) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL9382793 | 0.84 | POLB (0.44) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL10680107 | 0.83 | MEN1 (0.51) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL9520397 | 0.83 | KCNH2 (0.46) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL10680080 | 0.82 | CACNA1F (0.50) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL10679828 | 0.82 | KCNH2 (0.50) | POLBMAPK1CACNA1FCACNA1DKCNH2 | |
| SCHEMBL10680718 | 0.82 | POLB (0.54) | POLBMAPK1CACNA1FCACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226961-B1 | 5-AMINO AND 5-HYDROXY-6,8-DIFLUOROQUINOLONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | claimed |