Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875522 | 0.93 | KCNH2 (0.60) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9839457 | 0.91 | ALDH1A1 (0.50) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9837304 | 0.87 | KCNH2 (0.69) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9210716 | 0.87 | KCNH2 (0.49) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9435843 | 0.86 | MEN1 (0.57) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9837385 | 0.85 | POLB (0.45) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| Hydrochloric Acid SCHEMBL10686925 | 0.85 | MEN1 (0.56) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL9048301 | 0.83 | KCNH2 (0.53) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL8190975 | 0.83 | KCNH2 (0.74) | KCNH2POLBCACNA1FMAPK1CACNA1D | |
| SCHEMBL6561367 | 0.83 | KCNH2 (0.74) | KCNH2POLBCACNA1FMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226961-B1 | 5-AMINO AND 5-HYDROXY-6,8-DIFLUOROQUINOLONES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | claimed |