Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31448205 | 0.90 | GABRA1 (0.31) | GAAHTR4GABRA1GABRG2GABRB3 | |
| SCHEMBL10410194 | 0.89 | MEN1 (0.35) | GAALMNAHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL9521057 | 0.88 | GAA (0.38) | GAAHTR4GABRA1GABRG2GABRB3 | |
| SCHEMBL10410534 | 0.88 | SCN9A (0.36) | GAAHTR4LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6336900 | 0.88 | BAZ2B (0.46) | GAALMNAHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL10575497 | 0.87 | PPOX (0.36) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL9523236 | 0.87 | TP53 (0.38) | GAALMNAHPGDSMN1; SMN2MAPT | |
| SCHEMBL9494742 | 0.86 | GUSB (0.36) | GAAHTR4LMNAHPGDSMN1; SMN2 | |
| SCHEMBL26942116 | 0.86 | GAA (0.40) | GAALMNAHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL9523121 | 0.85 | HPGD (0.35) | HTR3AHPGDSMN1; SMN2HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |