Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520570 | 0.88 | GAA (0.37) | GAAHTR4BAZ2BBAZ2AGABRA1 | |
| SCHEMBL9521362 | 0.86 | HTR7 (0.40) | GAASMN1; SMN2LMNAMAPTTP53 | |
| SCHEMBL9523079 | 0.84 | MEN1 (0.33) | GAABAZ2BBAZ2AHPGDSMN1; SMN2 | |
| SCHEMBL9521255 | 0.84 | HPGD (0.37) | HPGDSMN1; SMN2MAPTPPOXHTR3E | |
| SCHEMBL22745804 | 0.83 | MAPT (0.36) | GAABAZ2BBAZ2AGABRA1GABRG2 | |
| SCHEMBL9522986 | 0.83 | MAPT (0.38) | HPGDSMN1; SMN2MAPTPPOXTP53 | |
| SCHEMBL9521382 | 0.83 | MAPT (0.38) | HPGDSMN1; SMN2MAPTPPOXTP53 | |
| SCHEMBL9519865 | 0.82 | PPOX (0.35) | GAABAZ2BBAZ2AHPGDSMN1; SMN2 | |
| SCHEMBL9523489 | 0.81 | L3MBTL1 (0.40) | BAZ2BBAZ2ALMNAMAPTCYP1A2 | |
| SCHEMBL9468954 | 0.80 | MAPT (0.35) | BAZ2BBAZ2AHPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |