Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520239 | 0.92 | UBE2M (0.42) | UBE2MDCUN1D1CCR5MEN1KMT2A | |
| SCHEMBL9520608 | 0.89 | ALDH1A1 (0.40) | MEN1KMT2AHTTALDH1A1POLB | |
| SCHEMBL9519114 | 0.87 | UBE2M (0.39) | UBE2MDCUN1D1CCR5MEN1KMT2A | |
| SCHEMBL9520722 | 0.86 | UBE2M (0.40) | UBE2MDCUN1D1CCR5MEN1KMT2A | |
| SCHEMBL9521103 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2AHTTALDH1A1POLB | |
| SCHEMBL9522363 | 0.79 | CACNA1C (0.35) | UBE2MDCUN1D1CCR5TDP1L3MBTL1 | |
| SCHEMBL9519145 | 0.77 | MAPT (0.39) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL9518928 | 0.76 | TDP1 (0.35) | HTTALDH1A1POLBMAPTATM | |
| SCHEMBL9519450 | 0.75 | ALDH1A1 (0.36) | CCR5MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL9520681 | 0.75 | ATM (0.39) | CCR5MEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5061804-A | 3-thiopyrrolidine as chemical intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4963543-A | BACTERICIDES, TREATING INFECTIOUS DISEASES; THIENAMYCINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-16 | — | — | US | disclosed |
| EP-0280771-A1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |