Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 11/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879207 | 0.83 | FFAR1 (0.42) | FFAR1LIPGPPARGPPARAMAOA | |
| SCHEMBL9523616 | 0.81 | FFAR1 (0.42) | FFAR1LIPGPPARGPPARAMAOA | |
| SCHEMBL8139703 | 0.73 | PPARG (0.48) | FFAR1PPARGPPARA | |
| SCHEMBL7723276 | 0.72 | PPARG (0.42) | FFAR1PPARGPPARA | |
| SCHEMBL7879128 | 0.71 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL7877637 | 0.71 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL9274342 | 0.71 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL9286066 | 0.71 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL7877640 | 0.71 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL9520129 | 0.71 | PPARG (0.40) | FFAR1LIPGPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332332-B1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5130379-A | Anticholesterol agents and antidiabetic agents | PFIZER INC. (US) | 1992-07-14 | — | — | US | disclosed |
| US-5036079-A | Anticholesterol | PFIZER INC. (US) | 1991-07-30 | — | — | US | disclosed |
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |
| WO-1989008651-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |
| EP-0332332-A1 | Hypoglycemic thiazolidinedione derivatives | PFIZER INC. (US) | 1989-09-13 | — | — | EP | disclosed |