Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520696 | 0.83 | FFAR1 (0.41) | FFAR1PPARGLIPGMAOACISD1 | |
| SCHEMBL9523616 | 0.75 | FFAR1 (0.42) | FFAR1PPARGLIPGMAOACISD1 | |
| SCHEMBL9878986 | 0.70 | PPARG (0.47) | FFAR1PPARGALDH1A1NPSR1PPARA | |
| SCHEMBL9879239 | 0.70 | LIPG (0.38) | FFAR1PPARGLIPGMAOACISD1 | |
| SCHEMBL9878823 | 0.70 | PPARG (0.42) | FFAR1PPARGLIPGMAOACISD1 | |
| SCHEMBL5167615 | 0.70 | FFAR1 (0.51) | FFAR1PPARGMAOACISD1MAOB | |
| SCHEMBL9274342 | 0.69 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL7877637 | 0.69 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL7879128 | 0.69 | PPARG (0.47) | FFAR1PPARGPPARA | |
| SCHEMBL9286066 | 0.69 | PPARG (0.47) | FFAR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003474-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1991-03-21 | — | — | WO | disclosed |
| WO-1989008651-A1 | HYPOGLYCEMIC THIAZOLIDINEDIONE DERIVATIVES | PFIZER INC. (US) | 1989-09-21 | — | — | WO | disclosed |