SCHEMBL9520728

SCHEMBL9520728

Cc1csc2c(S(N)(=O)=O)c(C(N)=O)nn12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.36
MET P08581 1/20 0.36
LTK P29376 1/20 0.36
CDK9 P50750 1/20 0.36
PRKX P51817 1/20 0.36
LRRK2 Q5S007 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
CA2 P00918 5/20 0.31
CA9 Q16790 5/20 0.31
CA1 P00915 4/20 0.31
CA12 O43570 3/20 0.31
CA4 P22748 3/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
CA3 P07451 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517917 0.83 CA1 (0.39) CA2CA9CA1CA4KDM4E
SCHEMBL9517798 0.63 ALDH1A1 (0.39) CHEK1METLTKCDK9PRKX
SCHEMBL6671705 0.61 PIM3 (0.41) LTKCDK9CLK4KDM4ELMNA
SCHEMBL13485367 0.56
SCHEMBL26136432 0.56 CA2 (0.37) CA2CA9CA1CA12CA14
SCHEMBL9517209 0.56 ALDH1A1 (0.41) PTGS2KDM4EPKMALDH1A1HPGD
SCHEMBL27444582 0.55 TSHR (0.37) CA2CA9CA1CA12CA4
SCHEMBL10750547 0.55 L3MBTL1 (0.46) CA2KDM4ELMNAPKMALDH1A1
SCHEMBL3081863 0.55 ADORA2A (0.49) KDM4ELMNAADORA3PKMADORA2A
SCHEMBL10808265 0.55 CA2 (0.35) CA2CA9CA1CA12CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238070-B1 Sulfonylurea compounds, their production and herbicidal use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-29 EP disclosed
US-5017212-A For rice paddies TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-05-21 US disclosed
EP-0238070-A2 Sulfonylurea compounds, their production and herbicidal use Takeda Chemical Industries, Ltd. (JP) 1987-09-23 EP disclosed