Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490548 | 1.00 | P2RX7 (0.36) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL9490641 | 1.00 | P2RX7 (0.36) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL9521621 | 0.90 | SLC6A2 (0.36) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL9491683 | 0.89 | P2RX7 (0.35) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL10431870 | 0.89 | P2RX7 (0.35) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL9521077 | 0.89 | ALDH1A1 (0.41) | ALDH1A1ITGA4ITGB7HTTCNR2 | |
| SCHEMBL9490387 | 0.89 | ALDH1A1 (0.41) | ALDH1A1ITGA4ITGB7HTTCNR2 | |
| SCHEMBL9491888 | 0.89 | ITGA4 (0.37) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL9491904 | 0.89 | P2RX7 (0.35) | P2RX7ALDH1A1SLC6A2SLC6A4ITGA4 | |
| SCHEMBL9490368 | 0.88 | CNR2 (0.41) | P2RX7ALDH1A1ITGA4ITGB7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |
| EP-0390693-A1 | Thioformamide derivatives | RHONE-POULENC SANTE (FR) | 1990-10-03 | — | — | EP | disclosed |