Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987246 | 0.81 | LTB4R (0.65) | LTB4RLTB4R2 | |
| SCHEMBL6759592 | 0.80 | LTB4R (0.68) | LTB4RLTB4R2 | |
| SCHEMBL6757532 | 0.75 | LTB4R (0.69) | LTB4RLTB4R2 | |
| Ammonia Solution, Strong SCHEMBL6757534 | 0.74 | LTB4R (0.73) | LTB4RLTB4R2 | |
| SCHEMBL9521475 | 0.72 | LTB4R (0.76) | LTB4R | |
| SCHEMBL8987273 | 0.72 | LTB4R (0.65) | LTB4RLTB4R2 | |
| SCHEMBL4348705 | 0.72 | LTB4R (1.00) | LTB4RLTB4R2 | |
| SCHEMBL8987236 | 0.71 | LTB4R (0.67) | LTB4RLTB4R2 | |
| SCHEMBL7110386 | 0.70 | LTB4R (0.68) | LTB4RLTB4R2 | |
| SCHEMBL6759758 | 0.70 | LTB4R (0.67) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |