SCHEMBL8987246

SCHEMBL8987246

c1ccc(-c2cc(OCCCCCc3nnn[nH]3)nc(-c3ccccc3)c2)cc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.65
LTB4R2 Q9NPC1 2/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987273 0.86 LTB4R (0.65) LTB4RLTB4R2
SCHEMBL9520945 0.81 LTB4R (0.56) LTB4RLTB4R2
SCHEMBL8987159 0.80 LTB4R (0.67) LTB4RLTB4R2
SCHEMBL6759592 0.78 LTB4R (0.68) LTB4RLTB4R2
SCHEMBL6757528 0.76 LTB4R (0.71) LTB4RLTB4R2
SCHEMBL6756180 0.76 LTB4R (0.73) LTB4RLTB4R2
SCHEMBL6946055 0.74 LTB4R (0.68) LTB4RLTB4R2
SCHEMBL7110386 0.74 LTB4R (0.68) LTB4RLTB4R2
SCHEMBL8987267 0.73 LTB4R (0.62) LTB4RLTB4R2
SCHEMBL8987368 0.73 LTB4R (0.72) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109069664-B anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates 苏特罗生物制药公司 2022-05-13 CN disclosed
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed
EP-0540604-A1 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS Aventis Pharma S.A. (FR) 1993-05-12 EP disclosed
WO-1992001675-A2 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS RHONE-POULENC RORER S.A. (FR) 1992-02-06 WO disclosed