Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521056 | 0.89 | DPP8 (0.41) | ATMTDP1RAB9AALDH1A1ECE1 | |
| SCHEMBL9519248 | 0.88 | ATM (0.41) | ATMTDP1RAB9AECE1NPC1 | |
| SCHEMBL9519252 | 0.88 | ATM (0.38) | ATMTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL8758724 | 0.86 | ATM (0.44) | ATMTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL8759542 | 0.86 | ATM (0.44) | ATMTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL9519787 | 0.85 | ATM (0.41) | ATMTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL9520047 | 0.83 | ATM (0.39) | ATMTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL9519209 | 0.83 | HTT (0.40) | ATMTDP1RAB9AALDH1A1MAPT | |
| SCHEMBL6945381 | 0.82 | ATM (0.45) | ATMTDP1RAB9AALDH1A1NPC1 | |
| SCHEMBL8759392 | 0.81 | ECE1 (0.42) | ATMTDP1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280771-B1 | 3-Pyrrolidinylthio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid derivatives and processes for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |