Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11019743 | 0.83 | SERPINA6 (0.70) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL4116607 | 0.76 | CYP3A4 (0.71) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL13752655 | 0.76 | CYP3A4 (0.71) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL4116602 | 0.76 | CYP3A4 (0.71) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL11702055 | 0.76 | LMNA (0.54) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL8938537 | 0.76 | LMNA (0.54) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL11021232 | 0.74 | SERPINA6 (0.50) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL11022201 | 0.71 | SERPINA6 (0.47) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL4751113 | 0.71 | SERPINA6 (0.67) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 | |
| SCHEMBL11020224 | 0.70 | SERPINA6 (0.62) | CYP19A1SHBGSERPINA6CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566566-A1 | COMPOSITIONS AND METHODS FOR ALLEVIATING MENOPAUSAL SYMPTOMS. | APPLIED MED RES LTD (US) | 1993-10-27 | — | — | EP | disclosed |
| WO-1992011855-A1 | COMPOSITIONS AND METHODS FOR ALLEVIATING MENOPAUSAL SYMPTOMS | APPLIED MEDICAL RESEARCH, LTD. (US) | 1992-07-23 | — | — | WO | disclosed |