Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SHBG | P04278 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702055 | 1.00 | LMNA (0.54) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL15730389 | 0.82 | LMNA (0.78) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL11020866 | 0.81 | PGR (0.60) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL11019743 | 0.80 | SERPINA6 (0.70) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL11022656 | 0.79 | LMNA (0.57) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL8938533 | 0.76 | LMNA (0.52) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL9521149 | 0.76 | CYP19A1 (0.52) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL4116607 | 0.71 | CYP3A4 (0.71) | LMNANR3C1MAPTCYP3A4PGR | |
| SCHEMBL4116602 | 0.71 | CYP3A4 (0.71) | LMNANR3C1MAPTCYP3A4PGR | |
| SCHEMBL13752655 | 0.71 | CYP3A4 (0.71) | LMNANR3C1MAPTCYP3A4PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7304793-A | — | — | None | — | — | JP | disclosed |
| US-5519153-A | Medrogestone production | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-05-21 | — | — | US | disclosed |
| JP-H07304793-A | PRODUCTION OF MEDROGESTRONE | AMERICAN HOME PROD CORP | 1995-11-21 | — | — | JP | disclosed |