Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520961 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2ADYRK1ADYRK2 | |
| SCHEMBL7711784 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL1309879 | 0.72 | HSP90AA1 (0.61) | ALDH1A1MAPTKMT2AMEN1HTT | |
| SCHEMBL9523023 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2ADYRK1ADYRK2 | |
| SCHEMBL307134 | 0.69 | ERN1 (0.65) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL11828282 | 0.68 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1DYRK1A | |
| SCHEMBL5035485 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL12236614 | 0.68 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL13689920 | 0.68 | HSD17B10 (0.62) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL16951936 | 0.68 | HSD17B10 (0.62) | ALDH1A1MAPTKMT2AMEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345637-B1 | N-SUBSTITUTED 3,4,5,6-TETRAHYDROPHTHALIMIDE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-4959098-A | HERBICIDES, PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| EP-0345637-A1 | N-substituted 3,4,5,6-tetrahydrophthalimide derivatives | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |