Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 5/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713370 | 0.80 | DYRK1A (0.39) | DYRK1ADYRK1BDYRK2PPOXCLK1 | |
| SCHEMBL9520173 | 0.79 | GRM7 (0.39) | — | |
| SCHEMBL9521001 | 0.79 | PPOX (0.38) | DYRK1APPOXKMT2AMAPT | |
| SCHEMBL7162462 | 0.78 | PPOX (0.45) | ALDH1A1DYRK1APPOXKMT2ARAD51 | |
| SCHEMBL9520961 | 0.74 | ALDH1A1 (0.47) | ALDH1A1DYRK1ADYRK1BDYRK2CLK1 | |
| SCHEMBL24293381 | 0.73 | PPOX (0.40) | ALDH1A1PPOXKMT2ARAD51MAPT | |
| SCHEMBL8011326 | 0.72 | PTGDR (0.42) | PPOX | |
| SCHEMBL8011328 | 0.72 | PTGDR (0.42) | PPOX | |
| SCHEMBL25395175 | 0.72 | PTGDR (0.42) | PPOX | |
| SCHEMBL9521155 | 0.71 | ALDH1A1 (0.48) | ALDH1A1DYRK1ADYRK1BDYRK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345637-B1 | N-SUBSTITUTED 3,4,5,6-TETRAHYDROPHTHALIMIDE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| US-4959098-A | HERBICIDES, PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-25 | — | — | US | disclosed |
| EP-0345637-A1 | N-substituted 3,4,5,6-tetrahydrophthalimide derivatives | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |