SCHEMBL307134

SCHEMBL307134

O=Cc1cc([N+](=O)[O-])ccc1Cl

nearest known ligand 0.65

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.65
HSD17B10 Q99714 1/20 0.64
AMY1A P0DUB6 1/20 0.54
VCAM1 P19320 2/20 0.53
KMT2A Q03164 3/20 0.51
MAPT P10636 4/20 0.51
HTT P42858 1/20 0.51
ALDH1A1 P00352 7/20 0.50
MEN1 O00255 2/20 0.50
POLB P06746 1/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
PTPN1 P18031 1/20 0.47
TDP1 Q9NUW8 3/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylformamide SCHEMBL27570110 0.90 ERN1 (0.54) ERN1HSD17B10AMY1AVCAM1KMT2A
SCHEMBL1195413 0.86 HSD17B10 (0.62) ERN1HSD17B10AMY1AVCAM1KMT2A
Glycine SCHEMBL8213987 0.86 ERN1 (0.54) ERN1HSD17B10AMY1AKMT2AMAPT
SCHEMBL6536285 0.84 ALDH1A1 (0.58) ERN1HSD17B10AMY1AVCAM1KMT2A
SCHEMBL2652355 0.83 ERN1 (0.69) ERN1HSD17B10KMT2AMAPTHTT
Cyclohexylamine SCHEMBL7792901 0.83 ERN1 (0.48) ERN1HSD17B10AMY1AKMT2AMAPT
SCHEMBL8700059 0.83 ERN1 (0.55) ERN1HSD17B10AMY1AVCAM1KMT2A
SCHEMBL13689920 0.82 HSD17B10 (0.62) ERN1HSD17B10AMY1AVCAM1KMT2A
SCHEMBL16951936 0.82 HSD17B10 (0.62) ERN1HSD17B10AMY1AVCAM1KMT2A
SCHEMBL9551019 0.82 HSD17B10 (0.56) ERN1HSD17B10AMY1AVCAM1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 972 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121379351-B Nano ceramic ultra-high hardness powder coating and preparation method thereof 广东桑瑞斯环保新材料有限公司 2026-05-12 CN claimed
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2024-02-29 US claimed
CN-113214182-B Benzisothiazole compound and preparation method thereof 佛山湘潭大学绿色智造研究院 2022-12-23 CN claimed
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2021-09-23 US claimed
CN-113214182-A Benzisothiazole compound and preparation method thereof 佛山湘潭大学绿色智造研究院 2021-08-06 CN claimed
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-06 US claimed
CN-103539789-A Preparation method of quinazoline derivative as tyrosine kinase inhibitor SOUTHEAST PHARMACEUTICALS CO LTD 2014-01-29 CN claimed
US-20060084176-A1 Detection of uronium salts YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-04-20 US claimed
US-20030175848-A1 Substituted dithiobisnitrobenzenes and their applications INSTITUT PASTEUR DE LILLE 2003-09-18 US claimed
EP-1082297-B1 SUBSTITUTED DITHIO-BIS-NITROBENZENES AND THEIR APPLICATIONS PASTEUR INSTITUT (FR) 2003-06-18 EP claimed
WO-1998034115-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
WO-1998002741-A9 QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES 1998-05-22 WO claimed
WO-1998002741-A1 QUINOLINE DERIVATIVES AND QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-01-22 WO claimed
EP-0461531-B1 Process for the purification of 2-chloro-5-nitrobenzaldehyde or their acetals BASF AG (DE) 1994-09-14 EP claimed
US-5149882-A PURIFICATION OF 2-CHLORO-5-NITROBENZALDEHYDE OR ACETALS THEREOF BASF AKTIENGESELLSCHAFT (DE) 1992-09-22 US claimed
EP-0461531-A2 Process for the purification of 2-chloro-5-nitrobenzaldehyde or their acetals BASF Aktiengesellschaft (DE) 1991-12-18 EP claimed
US-4456772-A Process for the preparation of optionally substituted fluoro-nitro-benzaldehydes BAYER AKTIENGESELLSCHAFT (DE) 1984-06-26 US claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed
US-3951993-A HYPOTENSIVE, CORONARY VESSEL DILATORS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 ERN1 4509/4885HSD17B10 4210/4885AMY1A 4170/4885
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS ERN1 4304/4885HSD17B10 4375/4885AMY1A 4136/4885
US-20030175848-A1 Substituted dithiobisnitrobenzenes and their applications TST, TXN, NQO1 ERN1 3150/4885HSD17B10 459/4885AMY1A 4040/4885
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS ERN1 4304/4885HSD17B10 4375/4885AMY1A 4136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.