Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521395 | 0.88 | ADRA1A (0.41) | SMN1; SMN2GAAADRA1APDE4DALDH1A1 | |
| SCHEMBL9521689 | 0.87 | POLB (0.45) | SMN1; SMN2ADRA1APDE4DALDH1A1NPC1 | |
| SCHEMBL9672860 | 0.85 | ADRA1A (0.62) | SMN1; SMN2GAAADRA1APDE4DALDH1A1 | |
| SCHEMBL9521622 | 0.84 | TRPV4 (0.43) | SMN1; SMN2NPC1RAB9AEPHX2 | |
| SCHEMBL8752193 | 0.81 | NPC1 (0.49) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL8752214 | 0.81 | KMT2A (0.48) | SMN1; SMN2GAAADRA1APDE4DALDH1A1 | |
| SCHEMBL11464467 | 0.79 | SMN1; SMN2 (0.70) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL9520912 | 0.78 | MAPT (0.49) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL8805273 | 0.78 | SMN1; SMN2 (0.68) | SMN1; SMN2GAAALDH1A1NPC1RAB9A | |
| SCHEMBL9521064 | 0.77 | ADRA1A (0.60) | SMN1; SMN2GAAADRA1APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
| EP-0366614-A2 | Pharmaceutically active dithioketene derivatives | YUHAN CORPORATION, LTD. (KR) | 1990-05-02 | — | — | EP | disclosed |