Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521395 | 0.88 | ADRA1A (0.41) | POLBNPSR1ADRA1APDE4DMAPT | |
| SCHEMBL9521170 | 0.87 | SMN1; SMN2 (0.50) | NPSR1ADRA1APDE4DMAPTSMN1; SMN2 | |
| SCHEMBL9672872 | 0.86 | ADRA1A (0.59) | POLBNPSR1ADRA1APDE4DMAPT | |
| SCHEMBL9521622 | 0.84 | TRPV4 (0.43) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11064150 | 0.80 | POLB (0.52) | POLBNPSR1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9521765 | 0.77 | TRPV4 (0.43) | RAB9ANPC1 | |
| SCHEMBL9521064 | 0.75 | ADRA1A (0.60) | ADRA1APDE4DSMN1; SMN2TSHR | |
| SCHEMBL9521789 | 0.75 | CTSK (0.41) | POLBADRA1APDE4DSMN1; SMN2ALDH1A1 | |
| SCHEMBL8752193 | 0.74 | NPC1 (0.49) | POLBSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL9674389 | 0.74 | ADRA1A (0.60) | NPSR1ADRA1APDE4DMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |