Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 4/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384498 | 0.83 | HRH3 (0.59) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL5519875 | 0.83 | HRH3 (0.62) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL5526919 | 0.81 | HRH3 (0.66) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL7387284 | 0.81 | HRH3 (0.66) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL7983991 | 0.81 | HRH3 (0.66) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL12408526 | 0.81 | HRH3 (0.66) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL7986752 | 0.81 | ALDH1A1 (0.66) | HRH3MAPTALDH1A1HRH2HRH1 | |
| SCHEMBL920034 | 0.80 | MAOB (0.44) | MAOBCA12CA9MAOA | |
| SCHEMBL25433144 | 0.78 | DRD2 (0.53) | ALDH1A1MAOBCA12CA9MAOA | |
| SCHEMBL9786397 | 0.78 | MAPT (0.50) | MAPTALDH1A1MAOBCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523803-A1 | 1,2,4-Oxadiazolyl-phenoxy-alkylisoxazoles and their use as antiviral agents | STERLING WINTHROP INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5175177-A | 1,2,4-OXADIAZOLYL-PHENOXYALKYLISOXAZOLES AND THEIR USE AS ANTIVIRAL AGENTS | STERLING DRUG INC. (US) | 1992-12-29 | — | — | US | disclosed |