Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.52 |
| ▸ | NOS3 | P29474 | 3/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364029 | 0.87 | NOS2 (0.50) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL20487372 | 0.85 | NOS2 (0.44) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL10400012 | 0.82 | PTGS2 (0.53) | NOS2RAB9AMAPTTLR8ALDH1A1 | |
| SCHEMBL2623102 | 0.79 | NOS2 (0.54) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL19151377 | 0.75 | TP53 (0.42) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL20661460 | 0.75 | NOS2 (0.44) | NOS2NOS3NOS1 | |
| SCHEMBL2175144 | 0.75 | MAPT (0.52) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL7700304 | 0.74 | CNR1 (0.46) | RAB9ANPC1ALDH1A1 | |
| SCHEMBL4575378 | 0.74 | CNR1 (0.38) | NOS2NOS3NOS1RAB9ANPC1 | |
| SCHEMBL10492672 | 0.74 | CNR1 (0.38) | NOS2NOS3NOS1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2019576-A | — | — | None | — | — | JP | disclosed |
| JP-5163124-A | — | — | None | — | — | JP | disclosed |
| JP-H05163124-A | KERATIN FIBER DYEING COMPOSITION | KAO CORP | 1993-06-29 | — | — | JP | disclosed |
| JP-H0219576-A | DYEING COMPOSITION FOR KERATINOUS FIBER | KAO CORP | 1990-01-23 | — | — | JP | disclosed |
| US-3943125-A | Substituted tetraamino heterocyclic compounds, useful in the preparation of substituted polybenzimidazoles and poly-imidazopyrrolones | HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) | 1976-03-09 | — | — | US | disclosed |