Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521601 | 0.90 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EEGLN1 | |
| SCHEMBL9744895 | 0.79 | MAPT (0.45) | MAPTKMT2AMEN1KDM4EEGLN1 | |
| SCHEMBL9521690 | 0.78 | MAPT (0.38) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8531170 | 0.78 | ADRA1A (0.46) | MAPTKMT2AMEN1KDM4EEGLN1 | |
| SCHEMBL9521958 | 0.76 | ADRA1A (0.34) | MAPT | |
| SCHEMBL9520606 | 0.76 | — | — | |
| SCHEMBL9520335 | 0.75 | MEN1 (0.33) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9521372 | 0.74 | ADRA1A (0.50) | KMT2ASMN1; SMN2TSHR | |
| SCHEMBL6356446 | 0.70 | GRIK1 (0.39) | MAPTKMT2AMEN1KDM4EEGLN1 | |
| SCHEMBL11616325 | 0.69 | ADRA1A (0.49) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |
| EP-0366614-A2 | Pharmaceutically active dithioketene derivatives | YUHAN CORPORATION, LTD. (KR) | 1990-05-02 | — | — | EP | disclosed |