Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976620 | 0.91 | NOTUM (0.34) | HPGDSMN1; SMN2NOTUMDHODHPOLB | |
| SCHEMBL9350427 | 0.82 | NOTUM (0.40) | HPGDSMN1; SMN2NOTUMPOLBAPEX1 | |
| SCHEMBL9878390 | 0.82 | HPGD (0.40) | HPGDDHODHPOLBAPEX1 | |
| SCHEMBL29449329 | 0.81 | POLB (0.32) | HPGDSMN1; SMN2DHODHPOLBAPEX1 | |
| SCHEMBL9423295 | 0.81 | POLB (0.32) | HPGDSMN1; SMN2DHODHPOLBAPEX1 | |
| SCHEMBL4404031 | 0.81 | POLB (0.32) | HPGDSMN1; SMN2DHODHPOLBAPEX1 | |
| SCHEMBL20356681 | 0.81 | NOTUM (0.36) | NOTUMMYCNR4A1CTSBTDP1 | |
| SCHEMBL31362249 | 0.81 | LMNA (0.34) | HPGDSMN1; SMN2POLBAPEX1 | |
| SCHEMBL9497444 | 0.81 | POLB (0.32) | HPGDSMN1; SMN2DHODHPOLBAPEX1 | |
| SCHEMBL9497450 | 0.81 | GRM4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323487-B1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-31 | — | — | EP | disclosed |
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-4941909-A | HERBICIDES, PYRIMIDONE BENZOATES | HOFFMANN-LA ROCHE INC. (US) | 1990-07-17 | — | — | US | disclosed |