Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522154 | 0.84 | MAPT (0.41) | RAB9AMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL9523113 | 0.76 | MEN1 (0.43) | RAB9AMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL9522166 | 0.76 | KMT2A (0.43) | RAB9AMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL9521967 | 0.75 | MAPT (0.41) | RAB9AMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL9522162 | 0.75 | RAB9A (0.43) | RAB9AMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL9522297 | 0.74 | HSD17B10 (0.40) | RAB9AMAPTALDH1A1KMT2ANPC1 | |
| SCHEMBL9522650 | 0.74 | CA12 (0.42) | RAB9AMAPTALDH1A1NPSR1NPC1 | |
| SCHEMBL9776526 | 0.73 | TXNRD1 (0.43) | MAPTALDH1A1KMT2AKDM4EHSD17B10 | |
| SCHEMBL9521955 | 0.73 | LOX (0.38) | RAB9AMAPTALDH1A1NPSR1KMT2A | |
| SCHEMBL9531992 | 0.72 | MAPT (0.48) | RAB9AMAPTALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4985432-A | 5H-1,3,4-thiadiazolo(3,2-A)pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |