Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 3/20 | 0.42 |
| ▸ | ALPI | P09923 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522297 | 0.83 | HSD17B10 (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9776596 | 0.82 | CA12 (0.40) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9525129 | 0.82 | ALDH1A1 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9521955 | 0.80 | LOX (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9523127 | 0.77 | ALDH1A1 (0.38) | HSD17B10ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9776603 | 0.75 | LMNA (0.38) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9521620 | 0.75 | ALDH1A1 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9522161 | 0.74 | RAB9A (0.39) | HSD17B10KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9531992 | 0.74 | MAPT (0.48) | CA12CA1CA2CA3CA4 | |
| SCHEMBL9522154 | 0.74 | MAPT (0.41) | HSD17B10KDM4EALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | claimed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | claimed |
| EP-0242690-B1 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-4985432-A | 5H-1,3,4-thiadiazolo(3,2-A)pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0242690-A2 | 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and agricultural-horticultural fungicide composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |