Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | TP53 | P04637 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522531 | 0.93 | MAPT (0.43) | MAPTTP53LMNAL3MBTL1 | |
| SCHEMBL9736649 | 0.89 | TP53 (0.42) | MAPTTP53LMNAL3MBTL1 | |
| SCHEMBL9256845 | 0.76 | PIK3CD (0.38) | MAPT | |
| SCHEMBL9523265 | 0.76 | TP53 (0.53) | MAPTTP53L3MBTL1 | |
| SCHEMBL9525860 | 0.74 | TP53 (0.38) | MAPTTP53LMNA | |
| SCHEMBL9525320 | 0.73 | ALDH1A1 (0.47) | MAPTTP53LMNA | |
| SCHEMBL9526026 | 0.73 | ALDH1A1 (0.48) | MAPTTP53 | |
| SCHEMBL14730 | 0.70 | CCNA2 (0.53) | MAPTTP53 | |
| SCHEMBL9834278 | 0.69 | TP53 (0.46) | MAPTTP53LMNA | |
| SCHEMBL12275859 | 0.69 | PIK3CD (0.46) | MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420883-B1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | ERBA CARLO SPA (IT) | 1993-11-03 | — | — | EP | disclosed |
| US-5166152-A | Immunostimulants, bactericides, viricides, antitumor agents | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-11-24 | — | — | US | disclosed |
| EP-0420883-A1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION. | ERBA CARLO SPA (IT) | 1991-04-10 | — | — | EP | disclosed |
| WO-1989012638-A1 | TRICYCLIC 3-OXO-PROPANENITRILE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-12-28 | — | — | WO | disclosed |