Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TOP1 | P11387 | 4/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674781 | 0.90 | PIM1 (0.49) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9522418 | 0.87 | PIM1 (0.45) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9232600 | 0.84 | KDM4E (0.46) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9673028 | 0.84 | LMNA (0.57) | KDM4EHPGDALDH1A1HSD17B10TOP1 | |
| SCHEMBL9672611 | 0.84 | PIM1 (0.48) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9568467 | 0.82 | GSK3B (0.36) | KDM4EHPGDTOP1PIM1GSK3A | |
| SCHEMBL9672628 | 0.81 | PIM1 (0.47) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9675220 | 0.81 | KDM4E (0.44) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9674743 | 0.80 | PIM1 (0.48) | KDM4EADRA2BMAPK1HPGDALDH1A1 | |
| SCHEMBL9525499 | 0.79 | LMNA (0.52) | KDM4EHPGDALDH1A1HSD17B10PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249043-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVES | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-4843070-A | BACTERIDCIDES, FUNGICIDES | NIPPON SHINYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0249043-A2 | Quinolinecarboxylic acid derivatives | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1987-12-16 | — | — | EP | disclosed |