Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 11/20 | 0.53 |
| ▸ | GUSB | P08236 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9522691 | 0.86 | CTSD (0.39) | CTSDGUSBKDM4EL3MBTL1 | |
| SCHEMBL20556851 | 0.84 | F2R (0.54) | CTSDGUSBHTTCYP1A2CYP2D6 | |
| SCHEMBL9522910 | 0.82 | LMNA (0.45) | CTSDKDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL9522281 | 0.81 | CTSD (0.52) | CTSDKDM4EALDH1A1HPGDHTT | |
| SCHEMBL9523067 | 0.80 | CTSD (0.47) | CTSDGUSBKDM4EHSD17B10CYP1A2 | |
| SCHEMBL4292873 | 0.78 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1HPGDAPEX1 | |
| SCHEMBL10466119 | 0.75 | CTSD (0.47) | CTSDGUSBKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL5121884 | 0.73 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL13610820 | 0.73 | ALDH1A1 (0.50) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL10556857 | 0.71 | HSD17B10 (0.43) | CTSDKDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129409-B1 | Thiazolo - and thiazinobenzimidazoles | WYETH JOHN & BROTHER LTD (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-4794123-A | Thiazolo- and thiazino- benzimidazoles and their use as anti-ulcer agents | JOHN WYETH & BROTHER LIMITED (GB) | 1988-12-27 | — | — | US | disclosed |
| US-4786636-A | ANTISECRETARY | JOHN WYETH & BROTHER LIMITED (GB) | 1988-11-22 | — | — | US | disclosed |
| US-4725605-A | Thiazolo- and thiazino-benzimidazoles, and their use as anti-ulcer/hypersecretion agents | JOHN WYETH & BROTHER LIMITED (GB) | 1988-02-16 | — | — | US | disclosed |
| EP-0129409-A2 | Thiazolo - and thiazinobenzimidazoles | JOHN WYETH & BROTHER LIMITED (GB) | 1984-12-27 | — | — | EP | disclosed |