Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191996 | 0.79 | TSHR (0.50) | LMNACA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL28568682 | 0.79 | TSHR (0.50) | LMNACA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL23849011 | 0.76 | LTA4H (0.47) | LMNA | |
| SCHEMBL13033618 | 0.76 | LMNA (0.39) | LMNACA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL6988170 | 0.74 | L3MBTL1 (0.50) | LMNACA1CA2ALDH1A1ZDHHC7 | |
| Hydrochloric Acid SCHEMBL30420218 | 0.74 | LTA4H (0.46) | LMNACA1CA2 | |
| SCHEMBL2166892 | 0.74 | — | — | |
| SCHEMBL27720640 | 0.72 | LMNA (0.43) | LMNAALDH1A1MAPTMMP2MMP9 | |
| SCHEMBL2376555 | 0.72 | FOLH1 (0.45) | CA1CA2SMN1; SMN2ZDHHC7TSHR | |
| SCHEMBL8705553 | 0.71 | SMN1; SMN2 (0.37) | CA1CA2SMN1; SMN2ZDHHC7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | claimed |