Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139123 | 0.84 | HSD17B1 (0.46) | HRH2HRH3CYP1A2CYP3A4CYP2A6 | |
| SCHEMBL10930599 | 0.82 | HRH3 (0.43) | MAOAMAOBCLK4KDM4EMAPK1 | |
| SCHEMBL1255427 | 0.81 | FFAR1 (0.44) | NCOA1NCOA3DYRK1ACLK4HRH2 | |
| SCHEMBL10932436 | 0.81 | NPC1 (0.42) | MAOAMAOBMAPK1HRH2HRH3 | |
| SCHEMBL9377137 | 0.79 | DYRK1A (0.50) | MAOBNCOA1NCOA3DYRK1ACLK4 | |
| SCHEMBL10930465 | 0.78 | SIGMAR1 (0.39) | NISCH | |
| SCHEMBL22849567 | 0.78 | HTR2C (0.50) | HTR1AHTR7CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13262848 | 0.78 | HTR1A (0.38) | HTR1AHTR7NISCH | |
| SCHEMBL11197977 | 0.76 | ESR2 (0.44) | HRH3 | |
| SCHEMBL10930612 | 0.75 | ESR2 (0.39) | HRH3NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5025075-A | — | — | None | — | — | JP | disclosed |
| JP-H0525075-A | M-SUBSTITUTED CYCLOHEXENYLPHENOL DERIVATIVE AND ITS PRODUCTION | FUJI PHOTO FILM CO LTD | 1993-02-02 | — | — | JP | disclosed |