⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943700 | 0.84 | — | — | |
| SCHEMBL20677323 | 0.81 | — | — | |
| SCHEMBL6434555 | 0.79 | — | — | |
| SCHEMBL11517580 | 0.76 | ALDH1A1 (0.38) | — | |
| SCHEMBL5868456 | 0.76 | SPHK2 (0.37) | — | |
| SCHEMBL5868453 | 0.76 | SPHK2 (0.37) | — | |
| SCHEMBL3622761 | 0.76 | — | — | |
| SCHEMBL28046889 | 0.75 | SPHK2 (0.36) | — | |
| SCHEMBL29013338 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL29013339 | 0.73 | LMNA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463061-B1 | CONTROLLED RELEASE DELIVERY DEVICE FOR MACROMOLECULAR PROTEINS | PITMAN-MOORE, INC. (US) | 1993-06-09 | — | — | EP | disclosed |
| EP-0463061-A1 | CONTROLLED RELEASE DELIVERY DEVICE FOR MACROMOLECULAR PROTEINS. | PITMAN MOORE INC (US) | 1992-01-02 | — | — | EP | disclosed |
| WO-1990011070-A1 | CONTROLLED RELEASE DELIVERY DEVICE FOR MACROMOLECULAR PROTEINS | PITMAN-MOORE, INC. (US) | 1990-10-04 | — | — | WO | disclosed |
| US-4292299-A | Slow-releasing medical preparation to be administered by adhering to a wet mucous surface | TEIJIN LIMITED (JP) | 1981-09-29 | — | — | US | disclosed |
| US-4177073-A | TO INCREASE VISCOSITY OF COATING SOLUTION | OJI PAPER CO., LTD. (JP) | 1979-12-04 | — | — | US | disclosed |