Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.63 |
| ▸ | SLC9A1 | P19634 | 7/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434097 | 0.84 | HCAR3 (0.59) | HCAR3SLC9A1MAPTNAMPT | |
| SCHEMBL19848522 | 0.80 | SLC9A1 (0.64) | HCAR3SLC9A1GRM2MAPTNAMPT | |
| SCHEMBL19848221 | 0.79 | SLC9A1 (0.62) | HCAR3SLC9A1GRM2MAPT | |
| SCHEMBL19848730 | 0.79 | SLC9A1 (0.62) | HCAR3SLC9A1GRM2MAPT | |
| SCHEMBL1939333 | 0.78 | HCAR3 (0.54) | HCAR3SLC9A1MAPT | |
| SCHEMBL6044071 | 0.77 | HCAR3 (1.00) | HCAR3SLC9A1PLA2G4A | |
| SCHEMBL9524513 | 0.77 | HCAR3 (0.50) | HCAR3SLC9A1 | |
| SCHEMBL19911503 | 0.77 | HCAR3 (0.59) | HCAR3SLC9A1GRM2MAPT | |
| SCHEMBL9523866 | 0.75 | HCAR3 (0.61) | HCAR3SLC9A1GRM2 | |
| SCHEMBL19848183 | 0.75 | HCAR3 (0.58) | HCAR3SLC9A1GRM2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293978-B1 | (1H-AZOL-1-YLMETHYL)SUBSTITUTED BENZOTRIAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-09-15 | — | — | EP | disclosed |
| US-5039677-A | Estrogen inhibitor | JANSSEN PHARMACEUTICA N.V. (CA) | 1991-08-13 | — | — | US | disclosed |
| US-4943574-A | AROMATASE INHIBITORS, ESTROGEN DISORDERS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| EP-0293978-A2 | (1H-azol-1-ylmethyl)substituted benzotriazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-12-07 | — | — | EP | disclosed |