Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534116 | 0.85 | LSS (0.49) | LSSPOLBHTTCYP3A4BAZ2B | |
| SCHEMBL9523080 | 0.85 | MMP1 (0.48) | POLBDRD3KMT2AMMP1DRD2 | |
| SCHEMBL8538842 | 0.84 | LSS (0.48) | LSSHTTCYP3A4BAZ2BDRD3 | |
| SCHEMBL8534755 | 0.82 | LSS (0.46) | LSSHTTCYP3A4BAZ2BDRD3 | |
| SCHEMBL8540635 | 0.82 | GPR119 (0.48) | LSSHTTCYP3A4BAZ2BDRD3 | |
| SCHEMBL8534752 | 0.81 | LSS (0.46) | LSSHTTCYP3A4BAZ2BDRD3 | |
| SCHEMBL9589824 | 0.81 | EPHX2 (0.46) | LSSHTTCYP3A4BAZ2BDRD3 | |
| SCHEMBL9523895 | 0.80 | CYP2C19 (0.60) | LSSHTTCYP3A4BAZ2BPLA2G2A | |
| SCHEMBL10562129 | 0.80 | LSS (0.60) | LSSHTTCYP3A4BAZ2BPLA2G2A | |
| SCHEMBL8540462 | 0.79 | GPR119 (0.45) | LSSHTTCYP3A4BAZ2BDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537201-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | claimed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | claimed |
| WO-1991019709-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-26 | — | — | WO | claimed |
| EP-0537201-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5189036-A | Cardiovascular agents; class III antiarrhythmic agents | SCHERING AG (DE) | 1993-02-23 | — | — | US | disclosed |
| WO-1991019709-A1 | IMIDAZOLYLBENZOYL SUBSTITUTED HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1991-12-26 | — | — | WO | disclosed |