Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997472 | 0.85 | GRM5 (0.53) | MAPTGRM5ALDH1A1CYP1A2ALOX12 | |
| SCHEMBL27324689 | 0.77 | GRM5 (0.47) | MAPTGRM5ALDH1A1CYP1A2KDM4E | |
| SCHEMBL14085329 | 0.77 | CYP1A2 (0.49) | MAPTGRM5ALDH1A1CYP1A2KDM4E | |
| SCHEMBL17188595 | 0.75 | GRM5 (0.46) | MAPTGRM5ALDH1A1CYP1A2HTT | |
| SCHEMBL967014 | 0.75 | GRM5 (0.46) | MAPTGRM5ALDH1A1CYP1A2HTT | |
| SCHEMBL9522950 | 0.74 | ALDH1A1 (0.38) | MAPTALDH1A1CYP1A2KDM4EMAPK1 | |
| SCHEMBL2995424 | 0.74 | GRM5 (0.49) | MAPTGRM5ALDH1A1CYP1A2HTT | |
| SCHEMBL28558697 | 0.73 | GRM5 (0.49) | MAPTGRM5ALDH1A1CYP1A2HTT | |
| SCHEMBL28091793 | 0.72 | GRM5 (0.47) | MAPTGRM5ALDH1A1CYP1A2ALOX12 | |
| SCHEMBL968474 | 0.72 | GRM5 (0.47) | MAPTGRM5ALDH1A1CYP1A2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5025105-A | — | — | None | — | — | JP | disclosed |
| JP-H0525105-A | N-METHOXYBUTYNYLANILINE DERIVATIVE AND ITS PRODUCTION | CENTRAL GLASS CO LTD | 1993-02-02 | — | — | JP | disclosed |