SCHEMBL9522950

SCHEMBL9522950

COCC#CCNc1c(C)cccc1C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 2/20 0.36
NFKB1 P19838 1/20 0.36
CYP2C19 P33261 1/20 0.36
NLRP3 Q96P20 1/20 0.36
MAPT P10636 3/20 0.34
SCN3A Q9NY46 3/20 0.34
LMNA P02545 3/20 0.34
SCN1A P35498 2/20 0.34
SCN2A Q99250 2/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9524082 0.74 MAPT (0.44) ALDH1A1MEN1KMT2ACYP1A2MAPT
SCHEMBL11310203 0.72 ALDH1A1 (0.45) ALDH1A1CYP1A2CYP2C19MAPTCYP3A4
SCHEMBL11149393 0.71 ACHE (0.41) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL11189843 0.71 TSHR (0.38) ALDH1A1L3MBTL1MEN1KMT2ACYP1A2
SCHEMBL5840221 0.69 MAPT (0.54) ALDH1A1L3MBTL1MEN1KMT2ACYP1A2
SCHEMBL1259718 0.69 MAPT (0.42) ALDH1A1L3MBTL1MEN1KMT2ACYP1A2
SCHEMBL11135495 0.69 NLRP3 (0.46) ALDH1A1L3MBTL1MEN1KMT2ACYP1A2
SCHEMBL1827736 0.68 CYP3A4 (0.43) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL27691961 0.67 TOP2A (0.46) ALDH1A1MEN1KMT2ACYP1A2CYP2C9
SCHEMBL11957877 0.66 POLB (0.43) ALDH1A1L3MBTL1MEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5025105-A None JP disclosed
JP-H0525105-A N-METHOXYBUTYNYLANILINE DERIVATIVE AND ITS PRODUCTION CENTRAL GLASS CO LTD 1993-02-02 JP disclosed